Brief
Pyrroloquinoline Quinone Disodium Salt (PQQ Disodium Salt) (CAS No. 122628-50-6) is a water-soluble, bioactive compound derived from Pyrroloquinoline Quinone (PQQ) — a redox cofactor known for its exceptional role in mitochondrial biogenesis, antioxidant protection, and neuroprotection. As a stabilized and more bioavailable form of PQQ, the disodium salt variant is widely used in nutraceuticals, functional foods, and anti-aging formulations. With potent cellular energy–enhancing and brain-supporting properties, PQQ Disodium Salt has become a leading ingredient in supplements that promote vitality, focus, and longevity.
What is PQQ?
Pyrroloquinoline Quinone Disodium Salt is the disodium form of PQQ, a redox cofactor that plays a vital role in cellular energy metabolism. Its chemical formula is C₁₄H₄N₂Na₂O₈, with a molecular weight of 374.17 g/mol. Compared to pure PQQ acid, the disodium salt form is more stable, water-soluble, and easier to absorb, making it ideal for dietary and pharmaceutical applications. Biologically, PQQ functions as a redox cycling molecule, repeatedly undergoing oxidation and reduction to neutralize free radicals and protect mitochondria from oxidative stress. It also promotes the growth of new mitochondria in aging cells, a rare property that distinguishes it from most antioxidants. Scientific studies have shown that PQQ Disodium Salt can enhance cognitive performance, support memory and learning, boost energy metabolism, and protect nerve cells from degeneration. Because of these benefits, PQQ is often categorized as a mitochondrial nutrient — a new class of compounds essential for long-term cellular health, energy production, and brain function.
What are the specifications?
▶ PQQ powder
Chemical Name: Pyrroloquinoline Quinone Disodium Salt
CAS No.: 122628-50-6
Molecular Formula: C14H4N2Na2O8
Molecular Weight: 374.17 g/mol
Purity: ≥ 98.0%
pH (1% aqueous solution): 6.0–8.0
Appearance: Reddish-brown to dark red crystalline powder
Solubility: Freely soluble in water; insoluble in ethanol and ether

What does PQQ do?
Key Benefits and Functions:
- Boosts cellular energy – Stimulates mitochondrial biogenesis and enhances ATP synthesis for sustained physical and mental performance.
- Supports brain health – Improves memory, focus, and cognitive function by protecting neurons from oxidative and excitotoxic damage.
- Protects the heart and vessels – Enhances cardiovascular function and reduces oxidative damage to endothelial cells.
- Potent antioxidant defense – Exhibits remarkable redox cycling activity, allowing each molecule to scavenge free radicals multiple times.
- Promotes longevity and resilience – Encourages mitochondrial renewal and reduces fatigue associated with aging or stress.
Applications:
- Dietary supplements targeting energy, brain function, and anti-aging
- Functional beverages for endurance and focus enhancement
- Nootropic formulas improving learning and memory
- Anti-fatigue and wellness products designed for mitochondrial health
Conclusion
Pyrroloquinoline Quinone Disodium Salt (PQQ Disodium Salt) represents a breakthrough in nutritional biochemistry, offering comprehensive support for cellular energy, brain performance, and healthy aging. Its enhanced solubility, stability, and bioavailability make it the preferred form of PQQ in modern nutraceutical formulations. By promoting mitochondrial health and protecting against oxidative stress, PQQ Disodium Salt stands as one of the most powerful and scientifically validated mitochondrial nutrients for maintaining energy, clarity, and longevity.
What packaging do we use?

Purchase Link:
https://www.corepurebio.com/product/cas-122628-50-6-pqq-pyrroloquinoline-quinone-disodium-salt/
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