Brief
Polydeoxyribonucleotide (PDRN) (CAS No. 100403-24-5) is a biologically active compound composed of low-molecular-weight DNA fragments extracted primarily from salmon (Oncorhynchus mykiss or Oncorhynchus keta). It is widely used in medical aesthetics, dermatology, wound care, and regenerative medicine for its proven ability to promote tissue repair, cell regeneration, and anti-inflammatory effects. PDRN is a key active ingredient in injectable skin boosters and regenerative skincare products.
What is Polydeoxyribonucleotide Powder?
Polydeoxyribonucleotide is a mixture of purified DNA fragments with molecular weights typically ranging from 50 to 1,500 kDa. These DNA chains act as a source of nucleotides and nucleosides, which support cellular repair and regeneration. Biologically, PDRN functions by activating the adenosine A2A receptor, leading to enhanced cell proliferation, angiogenesis, and collagen synthesis while reducing inflammation. Due to its high biocompatibility and low immunogenicity, PDRN is well tolerated by skin and connective tissues, making it suitable for both medical and cosmetic applications.
What are the specifications?
▶ Polydeoxyribonucleotide Powder
Product Name: Polydeoxyribonucleotide (PDRN)
CAS No.: 100403-24-5
Source: Salmon DNA
Molecular Weight Range: 50–1,500 kDa
pH: 5.0-10.0
Assay : ≥ 80.0%
Appearance: White to off-white powder or clear solution
Solubility: Soluble in water

What does Polydeoxyribonucleotide Powder do?
- Cosmetics Field
Wrinkle Improvement | Regenerative Anti-Aging | Barrier Repair | Anti-Inflammatory & Spot Reduction
- Pharmaceuticals Field | Medical Devices Field
Tissue Regeneration | Skin Regeneration | Cartilage Regeneration
- Food Field
Improves digestive mucosa | Slows aging
- Medical Devices Field
3D Structural Support | Skin Repair | Regenerative Anti-Aging
Conclusion
Polydeoxyribonucleotide (PDRN) is a scientifically validated regenerative bioactive that plays a critical role in skin repair, anti-aging, and tissue regeneration. With excellent biocompatibility and proven clinical efficacy, PDRN has become a cornerstone ingredient in modern aesthetic medicine and regenerative skincare, delivering visible improvements in skin quality, healing, and resilience.
What packaging do we use?

Purchase Link: