2-Deoxy-D-glucose

2-Deoxy-D-Glucose (2-DG) (CAS No. 154-17-6) is a synthetic glucose analog widely used in biochemical, pharmaceutical, and metabolic research. Structurally similar to D-glucose, 2-DG interferes with normal glucose metabolism, making it a valuable tool for studying glycolysis, cellular energy pathways, cancer metabolism, and viral replication mechanisms. Due to its ability to inhibit glucose utilization at the cellular level, 2-DG has attracted significant interest in oncology research, metabolic studies, and drug development.

Product Name 2-Deoxy-D-glucose
CAS No. 154-17-6
Specific optical rotation +45.0°–+47.5
Heavy metals 10ppm Max
Loss on Drying 1.0% Max
Melting point 158-163ºC
Assay 98.0%
Appearance White or almost white powder
Residue on ignition 0.2% Max
Shelf life 2 years when properly stored.

1. Pharmaceutical Applications

2-Deoxy-D-Glucose is mainly used in pharmaceutical and biomedical research as a glycolysis inhibitor. It is applied in oncology, virology, and metabolic studies to investigate cellular energy metabolism, tumor growth mechanisms, and glucose-dependent pathways.

 

2. Cosmetic Research Applications

In the cosmetic field, 2-Deoxy-D-Glucose is used only for experimental and in vitro research to study skin cell metabolism, glycation-related aging, and energy regulation mechanisms.

 

 

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